Efficacite d’un dispositif medical a base d’acide hyaluronique liposome contre la secheresse vulvo-vaginale
J.-M.Bohbota C.de BeIllovskya G.Bramib P.Maresc
Abstract
Objectives
Hyaluronic acid (HA) is present in the vulva) and vaginal conjonctive tissue. It possesses hydrating and healing properties and is indicated to treat menopause induced vulvo-vaginal atrophy. The goal of this study is to evaluate the efficacy of a medical device based on HA upon patients of different ages suffering from vulvo-vaginal dryness (VVD).
Methods
Tested product based on HA was applied 3 times a week for 84 days by 47 patients,
28 premenopausal young women (mean age: 32 years old) and 19 post-menopausal women (mean age: 57.5 years old) all suffering from VVD associated to spontaneous pain and dyspareunia. Clinical evaluations and Vaginal Health Index (VHS) were calculated at 0, 1 and 3 months.
Results
A significant clinical improvement (P < 0.001) occurred at 1 month (-25 % for dryness and —46 % for pain) and at 3 months (respectively —86 and —79 %). VHS was significantly improved (P < 0.001) from 30 % at 1 month to 72 % after 3 months.
Conclusion
Gel based on HA significantly decreases symptoms and clinical signs of VVD at all ages and represents a safe and efficient alternative to topical and/or systemic hormonal therapy after menopause.
